Cargando…

A proposal for a drug information database and text templates for generating package inserts

To prevent prescription errors caused by information systems, a database to store complete and accurate drug information in a user-friendly format is needed. In previous studies, the primary method for obtaining data stored in a database is to extract drug information from package inserts by employi...

Descripción completa

Detalles Bibliográficos
Autores principales: Okuya, Ryo, Kimura, Masaomi, Ohkura, Michiko, Tsuchiya, Fumito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733914/
https://www.ncbi.nlm.nih.gov/pubmed/23930079
http://dx.doi.org/10.2147/DHPS.S43303
_version_ 1782279431539130368
author Okuya, Ryo
Kimura, Masaomi
Ohkura, Michiko
Tsuchiya, Fumito
author_facet Okuya, Ryo
Kimura, Masaomi
Ohkura, Michiko
Tsuchiya, Fumito
author_sort Okuya, Ryo
collection PubMed
description To prevent prescription errors caused by information systems, a database to store complete and accurate drug information in a user-friendly format is needed. In previous studies, the primary method for obtaining data stored in a database is to extract drug information from package inserts by employing pattern matching or more sophisticated methods such as text mining. However, it is difficult to obtain a complete database because there is no strict rule concerning expressions used to describe drug information in package inserts. The authors’ strategy was to first build a database and then automatically generate package inserts by embedding data in the database using templates. To create this database, the support of pharmaceutical companies to input accurate data is required. It is expected that this system will work, because these companies can earn merit for newly developed drugs to decrease the effort to create package inserts from scratch. This study designed the table schemata for the database and text templates to generate the package inserts. To handle the variety of drug-specific information in the package inserts, this information in drug composition descriptions was replaced with labels and the replacement descriptions utilizing cluster analysis were analyzed. To improve the method by which frequently repeated ingredient information and/or supplementary information are stored, the method was modified by introducing repeat tags in the templates to indicate repetition and improving the insertion of data into the database. The validity of this method was confirmed by inputting the drug information described in existing package inserts and checking that the method could regenerate the descriptions in the original package insert. In future research, the table schemata and text templates will be extended to regenerate other information in the package inserts.
format Online
Article
Text
id pubmed-3733914
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-37339142013-08-08 A proposal for a drug information database and text templates for generating package inserts Okuya, Ryo Kimura, Masaomi Ohkura, Michiko Tsuchiya, Fumito Drug Healthc Patient Saf Original Research To prevent prescription errors caused by information systems, a database to store complete and accurate drug information in a user-friendly format is needed. In previous studies, the primary method for obtaining data stored in a database is to extract drug information from package inserts by employing pattern matching or more sophisticated methods such as text mining. However, it is difficult to obtain a complete database because there is no strict rule concerning expressions used to describe drug information in package inserts. The authors’ strategy was to first build a database and then automatically generate package inserts by embedding data in the database using templates. To create this database, the support of pharmaceutical companies to input accurate data is required. It is expected that this system will work, because these companies can earn merit for newly developed drugs to decrease the effort to create package inserts from scratch. This study designed the table schemata for the database and text templates to generate the package inserts. To handle the variety of drug-specific information in the package inserts, this information in drug composition descriptions was replaced with labels and the replacement descriptions utilizing cluster analysis were analyzed. To improve the method by which frequently repeated ingredient information and/or supplementary information are stored, the method was modified by introducing repeat tags in the templates to indicate repetition and improving the insertion of data into the database. The validity of this method was confirmed by inputting the drug information described in existing package inserts and checking that the method could regenerate the descriptions in the original package insert. In future research, the table schemata and text templates will be extended to regenerate other information in the package inserts. Dove Medical Press 2013-07-29 /pmc/articles/PMC3733914/ /pubmed/23930079 http://dx.doi.org/10.2147/DHPS.S43303 Text en © 2013 Okuya et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Okuya, Ryo
Kimura, Masaomi
Ohkura, Michiko
Tsuchiya, Fumito
A proposal for a drug information database and text templates for generating package inserts
title A proposal for a drug information database and text templates for generating package inserts
title_full A proposal for a drug information database and text templates for generating package inserts
title_fullStr A proposal for a drug information database and text templates for generating package inserts
title_full_unstemmed A proposal for a drug information database and text templates for generating package inserts
title_short A proposal for a drug information database and text templates for generating package inserts
title_sort proposal for a drug information database and text templates for generating package inserts
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733914/
https://www.ncbi.nlm.nih.gov/pubmed/23930079
http://dx.doi.org/10.2147/DHPS.S43303
work_keys_str_mv AT okuyaryo aproposalforadruginformationdatabaseandtexttemplatesforgeneratingpackageinserts
AT kimuramasaomi aproposalforadruginformationdatabaseandtexttemplatesforgeneratingpackageinserts
AT ohkuramichiko aproposalforadruginformationdatabaseandtexttemplatesforgeneratingpackageinserts
AT tsuchiyafumito aproposalforadruginformationdatabaseandtexttemplatesforgeneratingpackageinserts
AT okuyaryo proposalforadruginformationdatabaseandtexttemplatesforgeneratingpackageinserts
AT kimuramasaomi proposalforadruginformationdatabaseandtexttemplatesforgeneratingpackageinserts
AT ohkuramichiko proposalforadruginformationdatabaseandtexttemplatesforgeneratingpackageinserts
AT tsuchiyafumito proposalforadruginformationdatabaseandtexttemplatesforgeneratingpackageinserts