Heterologous Immunity Triggered by a Single, Latent Virus in Mus musculus: Combined Costimulation- and Adhesion- Blockade Decrease Rejection

The mechanisms underlying latent-virus-mediated heterologous immunity, and subsequent transplant rejection, especially in the setting of T cell costimulation blockade, remain undetermined. To address this, we have utilized MHV68 to develop a rodent model of latent virus-induced heterologous alloimmu...

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Detalles Bibliográficos
Autores principales: Beus, Jonathan M., Hashmi, Salila S., Selvaraj, Saranya A., Duan, Danxia, Stempora, Linda L., Monday, Stephanie A., Cheeseman, Jennifer A., Hamby, Kelly M., Speck, Samuel H., Larsen, Christian P., Kirk, Allan D., Kean, Leslie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733932/
https://www.ncbi.nlm.nih.gov/pubmed/23940724
http://dx.doi.org/10.1371/journal.pone.0071221

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