Neurotoxicity of Prion Peptides Mimicking the Central Domain of the Cellular Prion Protein

The physiological functions of PrP(C) remain enigmatic, but the central domain, comprising highly conserved regions of the protein may play an important role. Indeed, a large number of studies indicate that synthetic peptides containing residues 106–126 (CR) located in the central domain (CD, 95–133...

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Detalles Bibliográficos
Autores principales: Vilches, Silvia, Vergara, Cristina, Nicolás, Oriol, Sanclimens, Gloria, Merino, Sandra, Varón, Sonia, Acosta, Gerardo A., Albericio, Fernando, Royo, Miriam, Río, José A. Del, Gavín, Rosalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733940/
https://www.ncbi.nlm.nih.gov/pubmed/23940658
http://dx.doi.org/10.1371/journal.pone.0070881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733940/
https://www.ncbi.nlm.nih.gov/pubmed/23940658
http://dx.doi.org/10.1371/journal.pone.0070881

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