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Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation

BACKGROUND: Transforming growth factor beta (TGFβ) is transiently increased in the mammary gland during involution and by radiation. While TGFβ normally has a tumour suppressor role, prolonged exposure to TGFβ can induce an oncogenic epithelial to mesenchymal transition (EMT) program in permissive c...

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Detalles Bibliográficos
Autores principales:	Dunphy, Karen A, Seo, Jae-Hong, Kim, Daniel J, Roberts, Amy L, Tao, Luwei, DiRenzo, James, Balboni, Amanda L, Crisi, Giovanna M, Hagen, Mary J, Chandrasekaran, Thiruppavai, Gauger, Kelly J, Schneider, Sallie Smith, Jerry, D Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733955/ https://www.ncbi.nlm.nih.gov/pubmed/23883065 http://dx.doi.org/10.1186/1475-2867-13-74

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