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ERManI Is a Target of miR-125b and Promotes Transformation Phenotypes in Hepatocellular Carcinoma (HCC)
The MAN1B1 gene product, designated ER alpha-1, 2-mannosidase (ERManI), is an enzyme localized in the Golgi complex of mammalian cells. By functioning as a “gate keeper” to prevent the inappropriate secretion of misfolded glycoproteins, it plays a critical role in maintaining protein homeostasis in...
Autores principales: | Pan, Shujuan, Cheng, Xiaoyun, Chen, Hongan, Castro, Patricia D., Ittmann, Michael M., Hutson, Anne W., Zapata, Susan K., Sifers, Richard N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733964/ https://www.ncbi.nlm.nih.gov/pubmed/23940818 http://dx.doi.org/10.1371/journal.pone.0072829 |
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