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ERManI Is a Target of miR-125b and Promotes Transformation Phenotypes in Hepatocellular Carcinoma (HCC)

The MAN1B1 gene product, designated ER alpha-1, 2-mannosidase (ERManI), is an enzyme localized in the Golgi complex of mammalian cells. By functioning as a “gate keeper” to prevent the inappropriate secretion of misfolded glycoproteins, it plays a critical role in maintaining protein homeostasis in...

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Detalles Bibliográficos
Autores principales: Pan, Shujuan, Cheng, Xiaoyun, Chen, Hongan, Castro, Patricia D., Ittmann, Michael M., Hutson, Anne W., Zapata, Susan K., Sifers, Richard N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733964/
https://www.ncbi.nlm.nih.gov/pubmed/23940818
http://dx.doi.org/10.1371/journal.pone.0072829

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