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Schedule-dependent antitumor effects of 5-fluorouracil combined with sorafenib in hepatocellular carcinoma

BACKGROUND: Recently, a phase II clinical trial in hepatocellular carcinoma (HCC) has suggested that the combination of sorafenib and 5-fluorouracil (5-FU) is feasible and side effects are manageable. However, preclinical experimental data explaining the interaction mechanism(s) are lacking. Our obj...

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Detalles Bibliográficos
Autores principales:	Deng, Lifen, Ren, Zhenggang, Jia, Qingan, Wu, Weizhong, Shen, Hujia, Wang, Yanhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734040/ https://www.ncbi.nlm.nih.gov/pubmed/23895220 http://dx.doi.org/10.1186/1471-2407-13-363

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