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An ESCRT–spastin interaction promotes fission of recycling tubules from the endosome

Mechanisms coordinating endosomal degradation and recycling are poorly understood, as are the cellular roles of microtubule (MT) severing. We show that cells lacking the MT-severing protein spastin had increased tubulation of and defective receptor sorting through endosomal tubular recycling compart...

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Detalles Bibliográficos
Autores principales: Allison, Rachel, Lumb, Jennifer H., Fassier, Coralie, Connell, James W., Ten Martin, Daniel, Seaman, Matthew N.J., Hazan, Jamilé, Reid, Evan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734076/
https://www.ncbi.nlm.nih.gov/pubmed/23897888
http://dx.doi.org/10.1083/jcb.201211045