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JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

Regulation of the opposing kinesin and dynein motors that drive axonal transport is essential to maintain neuronal homeostasis. Here, we examine coordination of motor activity by the scaffolding protein JNK-interacting protein 1 (JIP1), which we find is required for long-range anterograde and retrog...

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Detalles Bibliográficos
Autores principales:	Fu, Meng-meng, Holzbaur, Erika L.F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734084/ https://www.ncbi.nlm.nih.gov/pubmed/23897889 http://dx.doi.org/10.1083/jcb.201302078

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