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Microtubule severing by the katanin complex is activated by PPFR-1–dependent MEI-1 dephosphorylation
Katanin is an evolutionarily conserved microtubule (MT)-severing complex implicated in multiple aspects of MT dynamics. In Caenorhabditis elegans, the katanin homologue MEI-1 is required for meiosis, but must be inactivated before mitosis. Here we show that PPFR-1, a regulatory subunit of a trimeric...
Autores principales: | Gomes, José-Eduardo, Tavernier, Nicolas, Richaudeau, Bénédicte, Formstecher, Etienne, Boulin, Thomas, Mains, Paul E., Dumont, Julien, Pintard, Lionel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734088/ https://www.ncbi.nlm.nih.gov/pubmed/23918937 http://dx.doi.org/10.1083/jcb.201304174 |
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