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Microtubule severing by the katanin complex is activated by PPFR-1–dependent MEI-1 dephosphorylation

Katanin is an evolutionarily conserved microtubule (MT)-severing complex implicated in multiple aspects of MT dynamics. In Caenorhabditis elegans, the katanin homologue MEI-1 is required for meiosis, but must be inactivated before mitosis. Here we show that PPFR-1, a regulatory subunit of a trimeric...

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Detalles Bibliográficos
Autores principales: Gomes, José-Eduardo, Tavernier, Nicolas, Richaudeau, Bénédicte, Formstecher, Etienne, Boulin, Thomas, Mains, Paul E., Dumont, Julien, Pintard, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734088/
https://www.ncbi.nlm.nih.gov/pubmed/23918937
http://dx.doi.org/10.1083/jcb.201304174

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