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A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
DNA double-strand breaks (DSBs) are the most toxic of all genomic insults, and pathways dealing with their signaling and repair are crucial to prevent cancer and for immune system development. Despite intense investigations, our knowledge of these pathways has been technically limited by our inabili...
Autores principales: | Britton, Sébastien, Coates, Julia, Jackson, Stephen P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734090/ https://www.ncbi.nlm.nih.gov/pubmed/23897892 http://dx.doi.org/10.1083/jcb.201303073 |
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