MyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in Mice Infected with Treponema pallidum, the Agent of Syphilis

Research on syphilis, a sexually transmitted infection caused by the non-cultivatable spirochete Treponema pallidum, has been hampered by the lack of an inbred animal model. We hypothesized that Toll-like receptor (TLR)-dependent responses are essential for clearance of T. pallidum and, consequently...

Descripción completa

Detalles Bibliográficos
Autores principales: Silver, Adam C., Dunne, Dana W., Zeiss, Caroline J., Bockenstedt, Linda K., Radolf, Justin D., Salazar, Juan C., Fikrig, Erol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734110/
https://www.ncbi.nlm.nih.gov/pubmed/23940747
http://dx.doi.org/10.1371/journal.pone.0071388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734110/
https://www.ncbi.nlm.nih.gov/pubmed/23940747
http://dx.doi.org/10.1371/journal.pone.0071388

Ejemplares similares