Cargando…

Pirfenidone Nanoparticles Improve Corneal Wound Healing and Prevent Scarring Following Alkali Burn

PURPOSE: To evaluate the effects of pirfenidone nanoparticles on corneal re-epithelialization and scarring, major clinical challenges after alkali burn. METHODS: Effect of pirfenidone on collagen I and α-smooth muscle actin (α-SMA) synthesis by TGFβ induced primary corneal fibroblast cells was evalu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chowdhury, Sushovan, Guha, Rajdeep, Trivedi, Ruchit, Kompella, Uday B., Konar, Aditya, Hazra, Sarbani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734236/ https://www.ncbi.nlm.nih.gov/pubmed/23940587 http://dx.doi.org/10.1371/journal.pone.0070528

Ejemplares similares

Non-mulberry Silk Fibroin Biomaterial for Corneal Regeneration
por: Hazra, Sarbani, et al.
Publicado: (2016)

Effects of nicotine on corneal wound healing following acute alkali burn
por: Kim, Jong Won, et al.
Publicado: (2017)

The Wound Healing Effect of Doxycycline after Corneal Alkali Burn in Rats
por: Yi, Qiong, et al.
Publicado: (2019)

Topical Pirfenidone-Loaded Liposomes Ophthalmic Formulation Reduces Haze Development after Corneal Alkali Burn in Mice
por: Diaz-Palomera, Carlos Daniel, et al.
Publicado: (2022)

Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn
por: Bian, Fang, et al.
Publicado: (2017)

Topical Brazilian propolis improves corneal wound healing and inflammation in rats following alkali burns
por: Martin, Luiz Fernando Taranta, et al.
Publicado: (2013)

Scars, Burns and Healing
por: Shokrollahi, Kayvan
Publicado: (2016)

Molecular Mechanisms Related to Burns, Burn Wound Healing and Scarring
por: Kamolz, Lars-Peter, et al.
Publicado: (2023)

An in situ hydrogel based on carboxymethyl chitosan and sodium alginate dialdehyde for corneal wound healing after alkali burn
por: Xu, Wenhua, et al.
Publicado: (2018)

Heparin-Modified Amniotic Membrane Combined With Growth Factors for Promoting Corneal Wound Healing After Alkali Burn
por: Zhao, Xuan, et al.
Publicado: (2020)

Polysaccharide Hydrogel Combined with Mesenchymal Stem Cells Promotes the Healing of Corneal Alkali Burn in Rats
por: Ke, Yifeng, et al.
Publicado: (2015)

Topical Losartan and Corticosteroid Additively Inhibit Corneal Stromal Myofibroblast Generation and Scarring Fibrosis After Alkali Burn Injury
por: Sampaio, Lycia Pedral, et al.
Publicado: (2022)

Modulation of matrix metalloproteinase activity by EDTA prevents posterior capsular opacification
por: Hazra, Sarbani, et al.
Publicado: (2012)

Erratum in: Topical Losartan and Corticosteroid Additively Inhibit Corneal Stromal Myofibroblast Generation and Scarring Fibrosis After Alkali Burn Injury
Publicado: (2022)

Comparison of Corneal Epithelial Wound Healing between Topical RCI001, Solcoseryl, and Polydeoxyribonucleotide in the Murine Ocular Alkali Burn Model
por: Song, Myung-Sun, et al.
Publicado: (2023)

Minocycline Inhibits Alkali Burn-Induced Corneal Neovascularization in Mice
por: Xiao, Ou, et al.
Publicado: (2012)

Involvement of NADPH oxidases in alkali burn-induced corneal injury
por: GU, XUE-JUN, et al.
Publicado: (2016)

Inhibition of NUCKS Facilitates Corneal Recovery Following Alkali Burn
por: Poon, Ming-Wai, et al.
Publicado: (2017)

PEP-1-FK506BP inhibits alkali burn-induced corneal inflammation on the rat model of corneal alkali injury
por: Kim, Dae Won, et al.
Publicado: (2015)

Introducing video content into Scars, Burns & Healing
por: Tridente, Ascanio
Publicado: (2020)

Extracellular Matrix Deposition and Remodeling after Corneal Alkali Burn in Mice
por: Mutoji, Kazadi N., et al.
Publicado: (2021)

Topical Vitamin C Promotes the Recovery of Corneal Alkali Burns in Mice
por: Li, Min, et al.
Publicado: (2021)

Curative effect and possible mechanism of taurine on early corneal alkali burns
por: Tan, Yuan, et al.
Publicado: (2022)

Emerging Strategies in Treating Corneal Alkali Burns: A Narrative Review
por: Mittal, Mehul, et al.
Publicado: (2023)

Effect of pirfenidone on wound healing in lung transplant patients
por: Mortensen, Amber, et al.
Publicado: (2018)

Role of Mesenchymal Stem Cells on Cornea Wound Healing Induced by Acute Alkali Burn
por: Yao, Lin, et al.
Publicado: (2012)

Electrospun Fibers Loaded with Pirfenidone: An Innovative Approach for Scar Modulation in Complex Wounds
por: Tottoli, Erika Maria, et al.
Publicado: (2023)

Subconjunctival Injection of Regulatory T Cells Potentiates Corneal Healing Via Orchestrating Inflammation and Tissue Repair After Acute Alkali Burn
por: Yan, Dan, et al.
Publicado: (2020)

Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model
por: Kasamatsu, Momoko, et al.
Publicado: (2022)

MicroRNA-296 mediated corneal neovascularization in an animal model of corneal burns after alkali exposures
por: Ji, Kai-Bao, et al.
Publicado: (2018)

Effect of Collagen Cross-Linking on Alkali Burn-Induced Corneal Neovascularization in Rabbits
por: Xu, Xiaoying, et al.
Publicado: (2018)

Efficacy of systemic administration of riboflavin on a rabbit model of corneal alkali burn
por: Żuk, Maksym, et al.
Publicado: (2020)

The Therapeutic Effects and Possible Mechanism of Pranoprofen in Mouse Model of Corneal Alkali Burns
por: Chen, Minting, et al.
Publicado: (2020)

Rhamnazin attenuates inflammation and inhibits alkali burn-induced corneal neovascularization in rats
por: Yu, Yao, et al.
Publicado: (2018)

Current and Emerging Topical Scar Mitigation Therapies for Craniofacial Burn Wound Healing
por: Kwon, Sun Hyung, et al.
Publicado: (2020)

Treatment of scarring central airway stenosis with pirfenidone: Case report
por: Li, Xiao, et al.
Publicado: (2022)

Therapeutic Effects of Topical Netrin-4 Inhibits Corneal Neovascularization in Alkali-Burn Rats
por: Han, Yun, et al.
Publicado: (2015)

The molecular mechanisms of action of PPAR-γ agonists in the treatment of corneal alkali burns (Review)
por: Zhou, Hongyan, et al.
Publicado: (2016)

Ferrostatin‐1‐loaded liposome for treatment of corneal alkali burn via targeting ferroptosis
por: Wang, Kai, et al.
Publicado: (2021)

Wound Healing After Alkali Burn Injury of the Cornea Involves Nox4-Type NADPH Oxidase
por: Hakami, Nora Y., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9lbcn1rjr36sj3g66jgvmtnqrn