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Human Voltage-Gated Proton Channel Hv1: A New Potential Biomarker for Diagnosis and Prognosis of Colorectal Cancer

Solid tumors exist in a hypoxic microenvironment, and possess high-glycolytic metabolites. To avoid the acidosis, tumor cells must exhibit a dynamic cytosolic pH regulation mechanism(s). The voltage-gated proton channel Hv1 mediates NADPH oxidase function by compensating cellular loss of electrons w...

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Detalles Bibliográficos
Autores principales:	Wang, Yifan, Wu, Xingye, Li, Qiang, Zhang, Shangrong, Li, Shu Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734282/ https://www.ncbi.nlm.nih.gov/pubmed/23940591 http://dx.doi.org/10.1371/journal.pone.0070550

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