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mGluR5 Ablation in Cortical Glutamatergic Neurons Increases Novelty-Induced Locomotion

The group I metabotropic glutamate receptor 5 (mGluR5) has been implicated in the pathology of various neurological disorders including schizophrenia, ADHD, and autism. mGluR5-dependent synaptic plasticity has been described at a variety of neural connections and its signaling has been implicated in...

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Detalles Bibliográficos
Autores principales: Jew, Chris P., Wu, Chia-Shan, Sun, Hao, Zhu, Jie, Huang, Jui-Yen, Yu, Dinghui, Justice, Nicholas J., Lu, Hui-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734292/
https://www.ncbi.nlm.nih.gov/pubmed/23940572
http://dx.doi.org/10.1371/journal.pone.0070415