Mitochondrial Haplogroups Modify the Risk of Developing Hypertrophic Cardiomyopathy in a Danish Population

Hypertrophic cardiomyopathy (HCM) is a genetic disorder caused by mutations in genes coding for proteins involved in sarcomere function. The disease is associated with mitochondrial dysfunction. Evolutionarily developed variation in mitochondrial DNA (mtDNA), defining mtDNA haplogroups and haplogrou...

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Detalles Bibliográficos
Autores principales: Hagen, Christian M., Aidt, Frederik H., Hedley, Paula L., Jensen, Morten K., Havndrup, Ole, Kanters, Jørgen K., Moolman-Smook, Johanna C., Larsen, Severin O., Bundgaard, Henning, Christiansen, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734310/
https://www.ncbi.nlm.nih.gov/pubmed/23940792
http://dx.doi.org/10.1371/journal.pone.0071904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734310/
https://www.ncbi.nlm.nih.gov/pubmed/23940792
http://dx.doi.org/10.1371/journal.pone.0071904

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