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The mechanical uncoupler blebbistatin is associated with significant electrophysiological effects in the isolated rabbit heart
Blebbistatin (BS) is a recently discovered inhibitor of the myosin II isoform and has been adopted as the mechanical uncoupler of choice for optical mapping, because previous studies suggest that BS has no significant cardiac electrophysiological effects in a number of species. The aim of this study...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734628/ https://www.ncbi.nlm.nih.gov/pubmed/23291912 http://dx.doi.org/10.1113/expphysiol.2012.069369 |