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De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes

Double minutes (DMs) are hallmarks of gene amplification. However, their molecular structure and the mechanisms of formation are largely unknown. To elucidate the structure and underlying molecular mechanism of DMs, we obtained and cloned DMs using microdissection; and degenerated oligonucleotide pr...

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Detalles Bibliográficos
Autores principales: Zhu, Jing, Yu, Yang, Meng, Xiangning, Fan, Yihui, Zhang, Yu, Zhou, Chunshui, Yue, Zhichao, Jin, Yan, Zhang, Chunyu, Yu, Lisa, Ji, Wei, Jia, Xueyuan, Guan, Rongwei, Wu, Jie, Yu, Jingcui, Bai, Jing, Guan, Xin-Yuan, Wang, Mingrong, Lee, Ki-Young, Sun, Wenjing, Fu, Songbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734650/
https://www.ncbi.nlm.nih.gov/pubmed/23382041
http://dx.doi.org/10.1002/ijc.28084