Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment

This study, using mouse embryonic fibroblast (MEF) cells derived from ROCK1(−/−) and ROCK2(−/−) mice, is designed to dissect roles for ROCK1 and ROCK2 in regulating actin cytoskeleton reorganization induced by doxorubicin, a chemotherapeutic drug. ROCK1(−/−) MEFs exhibited improved actin cytoskeleto...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Jianjian, Wu, Xiangbing, Surma, Michelle, Vemula, Sasidhar, Zhang, Lumin, Yang, Yu, Kapur, Reuben, Wei, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734810/
https://www.ncbi.nlm.nih.gov/pubmed/23392171
http://dx.doi.org/10.1038/cddis.2013.10

Ejemplares similares

Ejemplares similares