TNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway

Activation of tumor necrosis factor receptor-1 can trigger survival or apoptosis pathways. In many cellular models, including the neuronal cell model PC12, it has been demonstrated that inhibition of protein synthesis is sufficient to render cells sensitive to apoptosis induced by TNFα. The survival...

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Detalles Bibliográficos
Autores principales: Marques-Fernandez, F, Planells-Ferrer, L, Gozzelino, R, Galenkamp, K MO, Reix, S, Llecha-Cano, N, Lopez-Soriano, J, Yuste, V J, Moubarak, R S, Comella, J X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734812/
https://www.ncbi.nlm.nih.gov/pubmed/23412386
http://dx.doi.org/10.1038/cddis.2013.25

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