Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death

Sensorineural hearing loss (SNHL) is one of the most common sensory defects in humans. Hair cells are vulnerable to various ototoxic insults. Effective prevention of hair cell loss remains an unmet medical need. Apoptotic hair cell death, which involves active regulation of transcription, accounts f...

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Detalles Bibliográficos
Autores principales: Yu, H, Lin, Q, Wang, Y, He, Y, Fu, S, Jiang, H, Yu, Y, Sun, S, Chen, Y, Shou, J, Li, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734817/
https://www.ncbi.nlm.nih.gov/pubmed/23429292
http://dx.doi.org/10.1038/cddis.2013.28

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