PKC signaling prevents irradiation-induced apoptosis of primary human fibroblasts

Primary cells respond to irradiation by activation of the DNA damage response and cell cycle arrest, which eventually leads to senescence or apoptosis. It is not clear in detail which signaling pathways or networks regulate the induction of either apoptosis or senescence. Primary human fibroblasts a...

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Detalles Bibliográficos
Autores principales: Bluwstein, A, Kumar, N, Léger, K, Traenkle, J, Oostrum, J van, Rehrauer, H, Baudis, M, Hottiger, M O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734826/
https://www.ncbi.nlm.nih.gov/pubmed/23412390
http://dx.doi.org/10.1038/cddis.2013.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734826/
https://www.ncbi.nlm.nih.gov/pubmed/23412390
http://dx.doi.org/10.1038/cddis.2013.15

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