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Manganese superoxide dismutase promotes anoikis resistance and tumor metastasis

Normal cells require adhesion to extracellular matrix for survival. Cell detachment causes a drastic increase in reactive oxygen species (ROS) that promotes anoikis. In the present study, we observed that upon detachment from matrix, human mammary epithelial cells strongly upregulate manganese super...

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Detalles Bibliográficos
Autores principales:	Kamarajugadda, S, Cai, Q, Chen, H, Nayak, S, Zhu, J, He, M, Jin, Y, Zhang, Y, Ai, L, Martin, S S, Tan, M, Lu, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734828/ https://www.ncbi.nlm.nih.gov/pubmed/23429290 http://dx.doi.org/10.1038/cddis.2013.20

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