Mutual regulation between DNA-PKcs and snail1 leads to increased genomic instability and aggressive tumor characteristics

Although the roles of DNA-dependent protein kinase catalytic subunits (DNA-PKcs) in the non-homologous end joining (NHEJ) of DNA repair are well-recognized, the biological mechanisms and regulators by DNA-PKcs besides DNA repair, have not been clearly described. Here, we show that active DNA-PKcs ca...

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Detalles Bibliográficos
Autores principales: Pyun, B-J, Seo, H R, Lee, H-J, Jin, Y B, Kim, E-J, Kim, N H, Kim, H S, Nam, H W, Yook, J I, Lee, Y-S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734834/
https://www.ncbi.nlm.nih.gov/pubmed/23449453
http://dx.doi.org/10.1038/cddis.2013.43

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