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eVolver: an optimization engine for evolving protein sequences to stabilize the respective structures

BACKGROUND: Many structural bioinformatics approaches employ sequence profile-based threading techniques. To improve fold recognition rates, homology searching may include artificially evolved amino acid sequences, which were demonstrated to enhance the sensitivity of protein threading in targeting...

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Detalles Bibliográficos
Autor principal: Brylinski, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735418/
https://www.ncbi.nlm.nih.gov/pubmed/23902875
http://dx.doi.org/10.1186/1756-0500-6-303