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Targeting beta-Catenin signaling to induce apoptosis in human breast cancer cells by z-Guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul

BACKGROUND: z-Guggulsterone (z-Gug) and Gugulipid (GL) have been used to treat a variety of ailments. We now report their anti-cancer effect and mechanism against human breast cancer. METHODS: Using the human estrogen receptor-positive (MCF-7) and triple-negative (MDA-MB-231) breast cancer cells as...

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Detalles Bibliográficos
Autores principales:	Jiang, Guoqin, Xiao, Xiao, Zeng, Yan, Nagabhushanam, Kalyanam, Majeed, Muhammed, Xiao, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735424/ https://www.ncbi.nlm.nih.gov/pubmed/23914993 http://dx.doi.org/10.1186/1472-6882-13-203

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