Par-1 Regulates Tissue Growth by Influencing Hippo Phosphorylation Status and Hippo-Salvador Association

The evolutionarily conserved Hippo (Hpo) signaling pathway plays a pivotal role in organ size control by balancing cell proliferation and cell death. Here, we reported the identification of Par-1 as a regulator of the Hpo signaling pathway using a gain-of-function EP screen in Drosophila melanogaste...

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Detalles Bibliográficos
Autores principales: Huang, Hong-Ling, Wang, Shimin, Yin, Meng-Xin, Dong, Liang, Wang, Chao, Wu, Wei, Lu, Yi, Feng, Miao, Dai, Chuanyang, Guo, Xiaocan, Li, Li, Zhao, Bin, Zhou, Zhaocai, Ji, Hongbin, Jiang, Jin, Zhao, Yun, Liu, Xin-Yuan, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735459/
https://www.ncbi.nlm.nih.gov/pubmed/23940457
http://dx.doi.org/10.1371/journal.pbio.1001620

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