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GATA-2 Transduces LPS-Induced il-1β Gene Expression in Macrophages via a Toll-Like Receptor 4/MD88/MAPK-Dependent Mechanism

Lipopolysaccharide (LPS) is a critical factor for inducing acute lung injury. GATA-2, a transcription factor, contributes to the control of cell activity and function. Exposure of RAW 264.7 cells to LPS induced interleukin (IL)-1β mRNA and protein expression and GATA-2 translocation from the cytopla...

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Detalles Bibliográficos
Autores principales:	Wu, Tsu-Tuan, Tai, Yu-Ting, Cherng, Yih-Giun, Chen, Tyng-Guey, Lin, Chien-Ju, Chen, Ta-Liang, Chang, Huai-Chia, Chen, Ruei-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735524/ https://www.ncbi.nlm.nih.gov/pubmed/23940812 http://dx.doi.org/10.1371/journal.pone.0072404

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