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Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System

Lesions in the DNA arise under ionizing irradiation conditions or various chemical oxidants as a single damage or as part of a multiply damaged site within 1–2 helical turns (clustered lesion). Here, we explored the repair opportunity of the apurinic/apyrimidinic site (AP site) composed of the clust...

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Detalles Bibliográficos
Autores principales: Belousova, Ekaterina A., Vasil'eva, Inna A., Moor, Nina A., Zatsepin, Timofey S., Oretskaya, Tatiana S., Lavrik, Olga I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735541/
https://www.ncbi.nlm.nih.gov/pubmed/23936307
http://dx.doi.org/10.1371/journal.pone.0068576

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