Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors

Vesicular stomatitis virus G glycoprotein (VSV-G) is the most widely used envelope protein for retroviral and lentiviral vector pseudotyping; however, serum inactivation of VSV-G pseudotyped vectors is a significant challenge for in vivo gene delivery. To address this problem, we conducted directed...

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Detalles Bibliográficos
Autores principales: Hwang, Bum-Yeol, Schaffer, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735647/
https://www.ncbi.nlm.nih.gov/pubmed/23364315
http://dx.doi.org/10.1038/gt.2013.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735647/
https://www.ncbi.nlm.nih.gov/pubmed/23364315
http://dx.doi.org/10.1038/gt.2013.1

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