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Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up

Background. Intracranial artery dissections are rare and many controversies exist about treatment options. The aim of this study was to evaluate the efficacy and safety of the endovascular approach in patients with an intracranial dissection presenting with different symptoms. Methods. We prospectiv...

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Autores principales: Mohammadian, Reza, Taheraghdam, Ali Akbar, Sharifipour, Ehsan, Mansourizadeh, Reza, Pashapour, Ali, Shimia, Mohammad, Shokouhi, Ghaffar, shakeri, Moslem, Hashemzadeh, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736402/
https://www.ncbi.nlm.nih.gov/pubmed/23970969
http://dx.doi.org/10.1155/2013/968380
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author Mohammadian, Reza
Taheraghdam, Ali Akbar
Sharifipour, Ehsan
Mansourizadeh, Reza
Pashapour, Ali
Shimia, Mohammad
Shokouhi, Ghaffar
shakeri, Moslem
Hashemzadeh, Ali
author_facet Mohammadian, Reza
Taheraghdam, Ali Akbar
Sharifipour, Ehsan
Mansourizadeh, Reza
Pashapour, Ali
Shimia, Mohammad
Shokouhi, Ghaffar
shakeri, Moslem
Hashemzadeh, Ali
author_sort Mohammadian, Reza
collection PubMed
description Background. Intracranial artery dissections are rare and many controversies exist about treatment options. The aim of this study was to evaluate the efficacy and safety of the endovascular approach in patients with an intracranial dissection presenting with different symptoms. Methods. We prospectively evaluated the clinical features and treatment outcomes of 30 patients who had angiographically confirmed nontraumatic intracranial dissections over 4 years. Patients were followed up for 17 months, and their final outcomes were assessed by the modified Rankin Score (mRS) and angiography. Results. Sixteen (53.3%) patients had a dissection of the anterior circulation, whereas 14 (46.7%) had a posterior circulation dissection. Overall, 83.3% of the patients suffered a subarachnoid hemorrhage (SAH). Grade IV Hunt and Hess score was seen in 32% of the SAH presenting cases. Parent artery occlusion (PAO) with coil embolization was used in 70% of the cases. The prevalence of overall procedural complications was 23.3%, and all were completely resolved at the end of follow-up. No evidence of in-stent occlusion/stenosis or rebleeding was observed in our cases during follow-up. Angiography results improved more frequently in the PAO with coil embolization group (100%) than in the stent-only-treated group (88.9%) (P = 0.310) and the unruptured dissection group (5/5, 100%) in comparison with the group that presented with SAH (95.8%) (P = 0.833). Conclusion. Favorable outcomes were achieved following an endovascular approach for symptomatic ruptured or unruptured dissecting aneurysms. However, the long-term efficacy and durability of these procedures remain to be determined in a larger series.
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spelling pubmed-37364022013-08-22 Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up Mohammadian, Reza Taheraghdam, Ali Akbar Sharifipour, Ehsan Mansourizadeh, Reza Pashapour, Ali Shimia, Mohammad Shokouhi, Ghaffar shakeri, Moslem Hashemzadeh, Ali Neurol Res Int Clinical Study Background. Intracranial artery dissections are rare and many controversies exist about treatment options. The aim of this study was to evaluate the efficacy and safety of the endovascular approach in patients with an intracranial dissection presenting with different symptoms. Methods. We prospectively evaluated the clinical features and treatment outcomes of 30 patients who had angiographically confirmed nontraumatic intracranial dissections over 4 years. Patients were followed up for 17 months, and their final outcomes were assessed by the modified Rankin Score (mRS) and angiography. Results. Sixteen (53.3%) patients had a dissection of the anterior circulation, whereas 14 (46.7%) had a posterior circulation dissection. Overall, 83.3% of the patients suffered a subarachnoid hemorrhage (SAH). Grade IV Hunt and Hess score was seen in 32% of the SAH presenting cases. Parent artery occlusion (PAO) with coil embolization was used in 70% of the cases. The prevalence of overall procedural complications was 23.3%, and all were completely resolved at the end of follow-up. No evidence of in-stent occlusion/stenosis or rebleeding was observed in our cases during follow-up. Angiography results improved more frequently in the PAO with coil embolization group (100%) than in the stent-only-treated group (88.9%) (P = 0.310) and the unruptured dissection group (5/5, 100%) in comparison with the group that presented with SAH (95.8%) (P = 0.833). Conclusion. Favorable outcomes were achieved following an endovascular approach for symptomatic ruptured or unruptured dissecting aneurysms. However, the long-term efficacy and durability of these procedures remain to be determined in a larger series. Hindawi Publishing Corporation 2013 2013-07-22 /pmc/articles/PMC3736402/ /pubmed/23970969 http://dx.doi.org/10.1155/2013/968380 Text en Copyright © 2013 Reza Mohammadian et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Mohammadian, Reza
Taheraghdam, Ali Akbar
Sharifipour, Ehsan
Mansourizadeh, Reza
Pashapour, Ali
Shimia, Mohammad
Shokouhi, Ghaffar
shakeri, Moslem
Hashemzadeh, Ali
Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up
title Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up
title_full Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up
title_fullStr Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up
title_full_unstemmed Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up
title_short Endovascular Treatment of Intracranial Artery Dissection: Clinical and Angiographic Follow-Up
title_sort endovascular treatment of intracranial artery dissection: clinical and angiographic follow-up
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736402/
https://www.ncbi.nlm.nih.gov/pubmed/23970969
http://dx.doi.org/10.1155/2013/968380
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