Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp

A new C(47) polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhi...

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Autores principales: Legrave, Nathalie, Hamrouni-Buonomo, Souhir, Dufies, Maeva, Guérineau, Vincent, Vacelet, Jean, Auberger, Patrick, Amade, Philippe, Mehiri, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736423/
https://www.ncbi.nlm.nih.gov/pubmed/23807547
http://dx.doi.org/10.3390/md11072282
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author Legrave, Nathalie
Hamrouni-Buonomo, Souhir
Dufies, Maeva
Guérineau, Vincent
Vacelet, Jean
Auberger, Patrick
Amade, Philippe
Mehiri, Mohamed
author_facet Legrave, Nathalie
Hamrouni-Buonomo, Souhir
Dufies, Maeva
Guérineau, Vincent
Vacelet, Jean
Auberger, Patrick
Amade, Philippe
Mehiri, Mohamed
author_sort Legrave, Nathalie
collection PubMed
description A new C(47) polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.
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spelling pubmed-37364232013-08-07 Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp Legrave, Nathalie Hamrouni-Buonomo, Souhir Dufies, Maeva Guérineau, Vincent Vacelet, Jean Auberger, Patrick Amade, Philippe Mehiri, Mohamed Mar Drugs Article A new C(47) polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines. MDPI 2013-06-27 /pmc/articles/PMC3736423/ /pubmed/23807547 http://dx.doi.org/10.3390/md11072282 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Legrave, Nathalie
Hamrouni-Buonomo, Souhir
Dufies, Maeva
Guérineau, Vincent
Vacelet, Jean
Auberger, Patrick
Amade, Philippe
Mehiri, Mohamed
Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp
title Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp
title_full Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp
title_fullStr Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp
title_full_unstemmed Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp
title_short Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp
title_sort nepheliosyne b, a new polyacetylenic acid from the new caledonian marine sponge niphates sp
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736423/
https://www.ncbi.nlm.nih.gov/pubmed/23807547
http://dx.doi.org/10.3390/md11072282
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