Sildenafil (Viagra) Protective Effects on Neuroinflammation: The Role of iNOS/NO System in an Inflammatory Demyelination Model

We recently demonstrated that sildenafil reduces the expression of cytokines, COX-2, and GFAP in a demyelinating model induced in wild-type (WT) mice. Herein, the understandings of the neuroprotective effect of sildenafil and the mediation of iNOS/NO system on inflammatory demyelination induced by c...

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Detalles Bibliográficos
Autores principales: Raposo, Catarina, Nunes, Ana Karolina de Santana, Luna, Rayana Leal de Almeida, Araújo, Shyrlene Meiry da Rocha, da Cruz-Höfling, Maria Alice, Peixoto, Christina Alves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736464/
https://www.ncbi.nlm.nih.gov/pubmed/23970812
http://dx.doi.org/10.1155/2013/321460

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