Cargando…

Potential of RAS Inhibition to Improve Metabolic Bone Disorders

Metabolic bone disorder is usually caused by abnormalities of minerals and hormones metabolism. Recently, it has been proved by several studies that the renin-angiotensin system (RAS) in local bone tissue is directly involved in bone metabolism. Activation of skeletal RAS plays an important role in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gebru, Yoseph, Diao, Teng-Yue, Pan, Hai, Mukwaya, Emmanuel, Zhang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736485/ https://www.ncbi.nlm.nih.gov/pubmed/23971050 http://dx.doi.org/10.1155/2013/932691

Ejemplares similares

Isolation and Characterization of Probiotic LAB from Kimchi and Spontaneously Fermented Teff (Eragrostis tef (Zucc.) Trotter) Batter: Their Effects on Phenolic Content of Teff during Fermentation
por: Gebru, Yoseph Asmelash, et al.
Publicado: (2020)

Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket
por: Wallon, Lauren, et al.
Publicado: (2022)

Inhibition of RAS in diabetic nephropathy
por: Yacoub, Rabi, et al.
Publicado: (2015)

Graded inhibition of oncogenic Ras-signaling by multivalent Ras-binding domains
por: Augsten, Martin, et al.
Publicado: (2014)

Selective and noncovalent targeting of RAS mutants for inhibition and degradation
por: Teng, Kai Wen, et al.
Publicado: (2021)

Atorvastatin Inhibits High-Fat Diet-Induced Lipid Metabolism Disorders in Rats by Inhibiting Bacteroides Reduction and Improving Metabolism
por: Li, Huimin, et al.
Publicado: (2022)

Deletion of cyclooxygenase-2 inhibits K-ras–induced lung carcinogenesis
por: Pan, Yong, et al.
Publicado: (2015)

Ras signaling in aging and metabolic regulation
por: Slack, Cathy
Publicado: (2017)

Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling
por: Umstead, MaKendra, et al.
Publicado: (2017)

Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS
por: Ilter, Metehan, et al.
Publicado: (2022)

RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia
por: Decroocq, Justine, et al.
Publicado: (2022)

Relapse of pathological angiogenesis: functional role of the basement membrane and potential treatment strategies
por: Mukwaya, Anthony, et al.
Publicado: (2021)

Metabolic disorders of bone /
por: Paterson, Colin Ralston
Publicado: (1974)

Combined targeting of Arf1 and Ras potentiates anticancer activity for prostate cancer therapeutics
por: Lang, Liwei, et al.
Publicado: (2017)

Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling
por: Yelland, Tamas, et al.
Publicado: (2022)

Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies
por: Bueno, Anibal, et al.
Publicado: (2016)

The Identification and Quantitative Analysis of Unusual Keto-Carotenoids in Ripe Fruits of Maclura tricuspidate and Its Potential as a Valuable Source of Cryptocapsin
por: Kim, Jong-Kuk, et al.
Publicado: (2022)

Ras signaling regulates osteoprogenitor cell proliferation and bone formation
por: Papaioannou, Garyfallia, et al.
Publicado: (2016)

Ras and Wnt Interaction Contribute in Prostate Cancer Bone Metastasis
por: Lin, Shian-Ren, et al.
Publicado: (2020)

Dynamic regulation of RAS and RAS signaling
por: Kolch, Walter, et al.
Publicado: (2023)

Superoxide Inhibits Guanine Nucleotide Exchange Factor (GEF) Action on Ras, but not on Rho, through Desensitization of Ras to GEF
por: Wey, Michael, et al.
Publicado: (2014)

Mulberry polyphenol extracts attenuated senescence through inhibition of Ras/ERK via promoting Ras degradation in VSMC
por: Chen, Ching-Pei, et al.
Publicado: (2022)

Effect of Ras Inhibition in Hematopoiesis and BCR/ABL Leukemogenesis
por: Baum, Karina J, et al.
Publicado: (2008)

Ras Inhibition Induces Insulin Sensitivity and Glucose Uptake
por: Mor, Adi, et al.
Publicado: (2011)

Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition
por: Hanker, Ariella B, et al.
Publicado: (2009)

The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling
por: Cui, Yan, et al.
Publicado: (2019)

Jianpi Qingchang Bushen decoction improves inflammatory response and metabolic bone disorder in inflammatory bowel disease-induced bone loss
por: Zhang, Ya-Li, et al.
Publicado: (2022)

The Role of Mast Cells in Bone Metabolism and Bone Disorders
por: Ragipoglu, Deniz, et al.
Publicado: (2020)

Pharmacological or genetic inhibition of hypoxia signaling attenuates oncogenic RAS-induced cancer phenotypes
por: Zhu, Jun-yi, et al.
Publicado: (2021)

Blocking K-Ras Interaction With the Plasma Membrane Is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity
por: Henkels, Karen M., et al.
Publicado: (2021)

K-Ras prenylation as a potential anticancer target
por: Baranyi, Marcell, et al.
Publicado: (2020)

The oncoprotein H-Ras(V12 )increases mitochondrial metabolism
por: Telang, Sucheta, et al.
Publicado: (2007)

SUN-110 The Role Of RasD2 In Metabolism And Obesity
por: Fong, Vincent, et al.
Publicado: (2019)

The Metabolic Landscape of RAS-Driven Cancers from biology to therapy
por: Mukhopadhyay, Suman, et al.
Publicado: (2021)

Primer on the metabolic bone diseases and disorders of mineral metabolism /
Publicado: (1993)

Primer on the metabolic bone diseases and disorders of mineral metabolism /
Publicado: (1990)

Primer on the metabolic bone diseases and disorders of mineral metabolism
Publicado: (1999)

Primer on the metabolic bone diseases and disorders of mineral metabolism
por: Goswami, Ravinder
Publicado: (2016)

Thyroid disorders and bone mineral metabolism
por: Dhanwal, Dinesh Kumar
Publicado: (2011)

Bone Metabolism Disorder in Epileptic Children
por: NAKHAEE MOGHADAM, MAaryam, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tf4hs50gk5e9gmc2r2qehpn2ve