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Formulation and Mathematical Optimization of Controlled Release Calcium Alginate Micro Pellets of Frusemide
Objective. Frusemide loaded calcium alginate micropellets, an oral microparticulate delivery system, was statistically optimized exhibiting prolonged therapeutic action minimizing its adverse effects. Methods. Ionotropic Gelation technique was adopted employing 3(2) Factorial designs and keeping the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736541/ https://www.ncbi.nlm.nih.gov/pubmed/23971046 http://dx.doi.org/10.1155/2013/819674 |