Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy

AIM: To assess serum Cu/Zn SOD (Superoxide Dismutase) concentration in individuals with clinical depression. SUBJECTS AND METHODS: Serum from 36 individuals diagnosed with clinical depression and 18 healthy controls were tested for Cu/Zn SOD serum concentration using ELISAs. RESULTS: Serum Cu/Zn SOD...

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Detalles Bibliográficos
Autor principal: Russo, A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2010
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736885/
https://www.ncbi.nlm.nih.gov/pubmed/23966790
http://dx.doi.org/10.4137/NMI.S5044
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author Russo, A.J.
author_facet Russo, A.J.
author_sort Russo, A.J.
collection PubMed
description AIM: To assess serum Cu/Zn SOD (Superoxide Dismutase) concentration in individuals with clinical depression. SUBJECTS AND METHODS: Serum from 36 individuals diagnosed with clinical depression and 18 healthy controls were tested for Cu/Zn SOD serum concentration using ELISAs. RESULTS: Serum Cu/Zn SOD levels of depressed individuals (both with and without secondary anxiety) were significantly higher than age and gender similar controls. We also found that, post anti-oxidant therapy, Cu/Zn SOD levels normalized to the level of normal healthy controls. DISCUSSION: These results suggest an association between Cu/Zn SOD serum levels and clinical depression.
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spelling pubmed-37368852013-08-21 Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy Russo, A.J. Nutr Metab Insights Short Report AIM: To assess serum Cu/Zn SOD (Superoxide Dismutase) concentration in individuals with clinical depression. SUBJECTS AND METHODS: Serum from 36 individuals diagnosed with clinical depression and 18 healthy controls were tested for Cu/Zn SOD serum concentration using ELISAs. RESULTS: Serum Cu/Zn SOD levels of depressed individuals (both with and without secondary anxiety) were significantly higher than age and gender similar controls. We also found that, post anti-oxidant therapy, Cu/Zn SOD levels normalized to the level of normal healthy controls. DISCUSSION: These results suggest an association between Cu/Zn SOD serum levels and clinical depression. Libertas Academica 2010-06-17 /pmc/articles/PMC3736885/ /pubmed/23966790 http://dx.doi.org/10.4137/NMI.S5044 Text en © the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.
spellingShingle Short Report
Russo, A.J.
Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy
title Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy
title_full Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy
title_fullStr Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy
title_full_unstemmed Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy
title_short Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy
title_sort increased serum cu/zn sod in individuals with clinical depression normalizes after zinc and anti-oxidant therapy
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736885/
https://www.ncbi.nlm.nih.gov/pubmed/23966790
http://dx.doi.org/10.4137/NMI.S5044
work_keys_str_mv AT russoaj increasedserumcuznsodinindividualswithclinicaldepressionnormalizesafterzincandantioxidanttherapy

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