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Increased Glyoxalase-1 Levels in Fkbp5 Knockout Mice Caused by Glyoxalase-1 Gene Duplication
Fkbp5 is genetically linked to stress-related diseases. Fkbp5 knockout mice are available and widely used to explore the role of Fkbp5 in health and disease. We found that these mice carry a gene duplication of glyoxylase-1, which explains why glyoxylase-1 levels are increased in the Fkbp5 knockout...
Autores principales: | Kollmannsberger, Lorenz K., Gassen, Nils C., Bultmann, Andrea, Hartmann, Jakob, Weber, Peter, Schmidt, Mathias V., Rein, Theo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737170/ https://www.ncbi.nlm.nih.gov/pubmed/23733890 http://dx.doi.org/10.1534/g3.113.006445 |
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