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Salivary Gland Hypofunction in tyrosylprotein sulfotransferase-2 Knockout Mice Is Due to Primary Hypothyroidism

BACKGROUND: Protein-tyrosine sulfation is a post-translational modification of an unknown number of secreted and membrane proteins mediated by two known Golgi tyrosylprotein sulfotransferases (TPST-1 and TPST-2). We reported that Tpst2-/- mice have mild-moderate primary hypothyroidism, whereas Tpst1...

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Detalles Bibliográficos
Autores principales: Westmuckett, Andrew D., Siefert, Joseph C., Tesiram, Yasvir A., Pinson, David M., Moore, Kevin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737198/
https://www.ncbi.nlm.nih.gov/pubmed/23951251
http://dx.doi.org/10.1371/journal.pone.0071822