Diabetes-Induced Superoxide Anion and Breakdown of the Blood-Retinal Barrier: Role of the VEGF/uPAR Pathway

Diabetes-induced breakdown of the blood-retinal barrier (BRB) has been linked to hyperglycemia-induced expression of vascular endothelial growth factor (VEGF) and is likely mediated by an increase in oxidative stress. We have shown that VEGF increases permeability of retinal endothelial cells (REC)...

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Detalles Bibliográficos
Autores principales: El-Remessy, Azza B., Franklin, Telina, Ghaley, Nagla, Yang, Jinling, Brands, Michael W., Caldwell, Ruth B., Behzadian, Mohamed Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737203/
https://www.ncbi.nlm.nih.gov/pubmed/23951261
http://dx.doi.org/10.1371/journal.pone.0071868

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