Cargando…

Discovery and Validation of DNA Hypomethylation Biomarkers for Liver Cancer Using HRM-Specific Probes

Poor prognosis of hepatocellular carcinoma (HCC) associated with late diagnosis necessitates the development of early diagnostic biomarkers. We have previously delineated the landscape of DNA methylation in HCC patients unraveling the importance of promoter hypomethylation in activation of cancer- a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stefanska, Barbara, Bouzelmat, Aurelie, Huang, Jian, Suderman, Matthew, Hallett, Michael, Han, Ze-Guang, Al-Mahtab, Mamun, Akbar, Sheikh Mohammad Fazle, Khan, Wasif Ali, Raqib, Rubhana, Szyf, Moshe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737236/ https://www.ncbi.nlm.nih.gov/pubmed/23950870 http://dx.doi.org/10.1371/journal.pone.0068439

Ejemplares similares

EDITORIAL
por: Akbar, Sheikh Mohammad Fazle, et al.
Publicado: (2019)

The Journal in the Horizon of Asia and Europe
por: Fazle Akbar, Sheikh Mohammad, et al.
Publicado: (2018)

Cellular and Molecular Mechanisms of Pathogenic and Protective Immune Responses to SARS-CoV-2 and Implications of COVID-19 Vaccines
por: Akbar, Sheikh Mohammad Fazle, et al.
Publicado: (2023)

A common promoter hypomethylation signature in invasive breast, liver and prostate cancer cell lines reveals novel targets involved in cancer invasiveness
por: Cheishvili, David, et al.
Publicado: (2015)

Epidemiology of Hepatitis E Virus in an Urban Community in Dhaka City
por: Rahman, Salimur, et al.
Publicado: (2014)

Development of Therapeutic Vaccine for Chronic Hepatitis B: Concept, Cellular and Molecular Events, Design, Limitation, and Future Projection
por: Akbar, Sheikh Mohammad Fazle, et al.
Publicado: (2022)

Nobel Prize for the Discovery of Hepatitis B and C: A Brief History in Time
por: Al-Mahtab, Mamun, et al.
Publicado: (2020)

Unprecedented rise of monkeypox in Europe and America: Are Asian countries ready for a new outbreak during the ongoing COVID-19 pandemic?
por: Khan, Sakirul, et al.
Publicado: (2022)

Broad Epigenetic Signature of Maternal Care in the Brain of Adult Rats
por: McGowan, Patrick O., et al.
Publicado: (2011)

Differential DNA Methylation Regions in Cytokine and Transcription Factor Genomic Loci Associate with Childhood Physical Aggression
por: Provençal, Nadine, et al.
Publicado: (2013)

DNA Methylation Signature of Childhood Chronic Physical Aggression in T Cells of Both Men and Women
por: Guillemin, Claire, et al.
Publicado: (2014)

Antiviral Response across Genotypes after Treatment of Chronic Hepatitis B Patients with the Therapeutic Vaccine NASVAC or Pegylated Interferon
por: Al-Mahtab, Mamun, et al.
Publicado: (2023)

Development of Therapy Based on the Exploration of Biological Events Underlying the Pathogenetic Mechanisms of Chronic Hepatitis B Infection
por: Akbar, Sheikh Mohammad Fazle, et al.
Publicado: (2023)

Association of Childhood Chronic Physical Aggression with a DNA Methylation Signature in Adult Human T Cells
por: Provençal, Nadine, et al.
Publicado: (2014)

Recent downhill course of COVID-19 at Rohingya refugee camps in Bangladesh: Urgent action solicited
por: Khan, Sakirul, et al.
Publicado: (2021)

Dengue Infections during COVID-19 Period: Reflection of Reality or Elusive Data Due to Effect of Pandemic
por: Khan, Sakirul, et al.
Publicado: (2022)

Strategic prospects for HRM
por: Tyson, Shaun
Publicado: (1995)

Methylated DNA Binding Domain Protein 2 (MBD2) Coordinately Silences Gene Expression through Activation of the MicroRNA hsa-mir-496 Promoter in Breast Cancer Cell Line
por: Alvarado, Sebastian, et al.
Publicado: (2013)

Shigella conjugate vaccine efficacy trial in controlled human model and potential immune correlates of protection
por: Raqib, Rubhana, et al.
Publicado: (2021)

Risk of congenital birth defects during COVID-19 pandemic: Draw attention to the physicians and policymakers
por: Khan, Md Sakirul Islam, et al.
Publicado: (2020)

Sustained Antiviral and Liver Protection by a Nasal Therapeutic Vaccine (NASVAC, Containing Both HBsAg and HBcAg) in Patients with Chronic Hepatitis B: 2-Year Follow-Up of Phase III Clinical Trial
por: Akbar, Sheikh Mohammad Fazle, et al.
Publicado: (2021)

Innovative Therapies Targeting the Virus and the Host for Treating Chronic Hepatitis B Virus Infection: From Bench to Bedside
por: Akbar, Sheikh Mohammad Fazle, et al.
Publicado: (2022)

Treatment of Nonalcoholic Steatohepatitis by Obeticholic Acid: Current Status
por: Roy, Partho Pratik, et al.
Publicado: (2022)

Safety profile, antiviral capacity, and liver protection of a nasal therapeutic vaccine in patients with chronic hepatitis B: Five-year-follow-up outcomes after the end of treatment
por: Al Mahtab, Mamun, et al.
Publicado: (2023)

Peripheral nerve injury is accompanied by chronic transcriptome-wide changes in the mouse prefrontal cortex
por: Alvarado, Sebastian, et al.
Publicado: (2013)

Childhood Chronic Physical Aggression Associates with Adult Cytokine Levels in Plasma
por: Provençal, Nadine, et al.
Publicado: (2013)

Hypomethylation of 111 Probes Predicts Poor Prognosis for Glioblastoma
por: Chen, Qi, et al.
Publicado: (2019)

Genomic analysis of Hepatitis B virus and its association with disease manifestations in Bangladesh
por: Raihan, Ruksana, et al.
Publicado: (2019)

The Safety and Efficacy of a Therapeutic Vaccine for Chronic Hepatitis B: A Follow-Up Study of Phase III Clinical Trial
por: Akbar, Sheikh Mohammad Fazle, et al.
Publicado: (2021)

Therapy Targeting Stem Cell in Patients with Decompensated Cirrhosis of Liver in a Tertiary Treatment Care Center of Bangladesh
por: Al Mahtab, Mamun, et al.
Publicado: (2017)

A Dynamic Mathematical Modeling Revelation about the Impact of Vaccination on Hepatitis B Virus-induced Infection and Death Rate in Bangladesh
por: Chakraborty, Sajib, et al.
Publicado: (2019)

A Case of Antimitochondrial Antibody Negative Primary Biliary Cirrhosis from Bangladesh and Review of Literature
por: Begum, Roksana, et al.
Publicado: (2015)

Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial)
por: Al Mahtab, Mamun, et al.
Publicado: (2018)

AI revolution in HRM: the new scorecard
por: Upadhyay, Ashwani Kumar, et al.
Publicado: (2020)

Integrated control of COVID-19 in resource-poor countries
por: Aziz, Asma B., et al.
Publicado: (2020)

Multilevel relational influences on HRM practices: a cross-country comparative reflective review of HRM practices in Asia
por: Malik, Ashish, et al.
Publicado: (2022)

Nature of Host Immunity during Hepatitis B Virus Infection and designing Immune Therapy
por: MF Akbar, Sheikh, et al.
Publicado: (2018)

Role of tenofovir and telbivudine in treatment of hepatitis B related acute on chronic liver failure
por: Malakar, Debraj, et al.
Publicado: (2021)

Hepatic Venous Pressure Gradient Measurement in Bangladeshi Cirrhotic Patients: A Correlation with Child’s Status, Variceal Size, and Bleeding
por: Al Mahtab, Mamun, et al.
Publicado: (2017)

An Outbreak of Acute Hepatitis in a Medical Facility of Bangladesh
por: Al Mahtab, Mamun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2b6iet6eife2fje8ahk5f44bno