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Segregation of a Latent High Adiposity Phenotype in Families with a History of Type 2 Diabetes Mellitus Implicates Rare Obesity-Susceptibility Genetic Variants with Large Effects in Diabetes-Related Obesity

BACKGROUND: We recently reported significantly greater weight gain in non-diabetic healthy subjects with a 1(st) degree family history (FH+) of type 2 diabetes mellitus (T2DM) than in a matched control group without such history (FH−) during voluntary overfeeding, implying co-inheritance of suscepti...

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Detalles Bibliográficos
Autores principales:	Jenkins, Arthur B., Batterham, Marijka, Samocha-Bonet, Dorit, Tonks, Katherine, Greenfield, Jerry R., Campbell, Lesley V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737254/ https://www.ncbi.nlm.nih.gov/pubmed/23950934 http://dx.doi.org/10.1371/journal.pone.0070435

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