Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: Implications for the treatment of human liver cancer

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide, with limited treatment options. AKT/mTOR and Ras/MAPK pathways are frequently deregulated in human hepatocarcinogenesis. Recently, we generated an animal model characterized by the co-expression of activat...

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Autores principales: Wang, Chunmei, Cigliano, Antonio, Delogu, Salvatore, Armbruster, Julia, Dombrowski, Frank, Evert, Matthias, Chen, Xin, Calvisi, Diego F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737302/
https://www.ncbi.nlm.nih.gov/pubmed/23759595
http://dx.doi.org/10.4161/cc.25099

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