Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

The nuclear receptor Rev-erb-α modulates hepatic lipid and glucose metabolism, adipogenesis and the inflammatory response in macrophages. We show here that Rev-erb-α is highly expressed in oxidative skeletal muscle and plays a role in mitochondrial biogenesis and oxidative function, in gain- and los...

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Detalles Bibliográficos
Autores principales: Woldt, Estelle, Sebti, Yasmine, Solt, Laura A., Duhem, Christian, Lancel, Steve, Eeckhoute, Jérôme, Hesselink, Matthijs K.C., Paquet, Charlotte, Delhaye, Stéphane, Shin, Youseung, Kamenecka, Theodore M., Schaart, Gert, Lefebvre, Philippe, Nevière, Rémi, Burris, Thomas P., Schrauwen, Patrick, Staels, Bart, Duez, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737409/
https://www.ncbi.nlm.nih.gov/pubmed/23852339
http://dx.doi.org/10.1038/nm.3213

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