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Mind the fish: zebrafish as a model in cognitive social neuroscience
Understanding how the brain implements social behavior on one hand, and how social processes feedback on the brain to promote fine-tuning of behavioral output according to changes in the social environment is a major challenge in contemporary neuroscience. A critical step to take this challenge succ...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737460/ https://www.ncbi.nlm.nih.gov/pubmed/23964204 http://dx.doi.org/10.3389/fncir.2013.00131 |
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author | Oliveira, Rui F. |
author_facet | Oliveira, Rui F. |
author_sort | Oliveira, Rui F. |
collection | PubMed |
description | Understanding how the brain implements social behavior on one hand, and how social processes feedback on the brain to promote fine-tuning of behavioral output according to changes in the social environment is a major challenge in contemporary neuroscience. A critical step to take this challenge successfully is finding the appropriate level of analysis when relating social to biological phenomena. Given the enormous complexity of both the neural networks of the brain and social systems, the use of a cognitive level of analysis (in an information processing perspective) is proposed here as an explanatory interface between brain and behavior. A conceptual framework for a cognitive approach to comparative social neuroscience is proposed, consisting of the following steps to be taken across different species with varying social systems: (1) identification of the functional building blocks of social skills; (2) identification of the cognitive mechanisms underlying the previously identified social skills; and (3) mapping these information processing mechanisms onto the brain. Teleost fish are presented here as a group of choice to develop this approach, given the diversity of social systems present in closely related species that allows for planned phylogenetic comparisons, and the availability of neurogenetic tools that allows the visualization and manipulation of selected neural circuits in model species such as the zebrafish. Finally, the state-of-the art of zebrafish social cognition and of the tools available to map social cognitive abilities to neural circuits in zebrafish are reviewed. |
format | Online Article Text |
id | pubmed-3737460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-37374602013-08-20 Mind the fish: zebrafish as a model in cognitive social neuroscience Oliveira, Rui F. Front Neural Circuits Neuroscience Understanding how the brain implements social behavior on one hand, and how social processes feedback on the brain to promote fine-tuning of behavioral output according to changes in the social environment is a major challenge in contemporary neuroscience. A critical step to take this challenge successfully is finding the appropriate level of analysis when relating social to biological phenomena. Given the enormous complexity of both the neural networks of the brain and social systems, the use of a cognitive level of analysis (in an information processing perspective) is proposed here as an explanatory interface between brain and behavior. A conceptual framework for a cognitive approach to comparative social neuroscience is proposed, consisting of the following steps to be taken across different species with varying social systems: (1) identification of the functional building blocks of social skills; (2) identification of the cognitive mechanisms underlying the previously identified social skills; and (3) mapping these information processing mechanisms onto the brain. Teleost fish are presented here as a group of choice to develop this approach, given the diversity of social systems present in closely related species that allows for planned phylogenetic comparisons, and the availability of neurogenetic tools that allows the visualization and manipulation of selected neural circuits in model species such as the zebrafish. Finally, the state-of-the art of zebrafish social cognition and of the tools available to map social cognitive abilities to neural circuits in zebrafish are reviewed. Frontiers Media S.A. 2013-08-08 /pmc/articles/PMC3737460/ /pubmed/23964204 http://dx.doi.org/10.3389/fncir.2013.00131 Text en Copyright © Oliveira. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Oliveira, Rui F. Mind the fish: zebrafish as a model in cognitive social neuroscience |
title | Mind the fish: zebrafish as a model in cognitive social neuroscience |
title_full | Mind the fish: zebrafish as a model in cognitive social neuroscience |
title_fullStr | Mind the fish: zebrafish as a model in cognitive social neuroscience |
title_full_unstemmed | Mind the fish: zebrafish as a model in cognitive social neuroscience |
title_short | Mind the fish: zebrafish as a model in cognitive social neuroscience |
title_sort | mind the fish: zebrafish as a model in cognitive social neuroscience |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737460/ https://www.ncbi.nlm.nih.gov/pubmed/23964204 http://dx.doi.org/10.3389/fncir.2013.00131 |
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