Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation

Macropinocytosis, a fluid-phase endocytosis, is a crucial pathway for antigen uptake and presentation in macrophages. We attempted to characterise the activation and deactivation of a small GTPase molecular switch, Rac1, in macropinocytosis using microscopic photo-manipulation. Expression of genetic...

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Detalles Bibliográficos
Autores principales: Fujii, Makoto, Kawai, Katsuhisa, Egami, Youhei, Araki, Nobukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737501/
https://www.ncbi.nlm.nih.gov/pubmed/23924974
http://dx.doi.org/10.1038/srep02385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737501/
https://www.ncbi.nlm.nih.gov/pubmed/23924974
http://dx.doi.org/10.1038/srep02385

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