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Structural and torsional properties of the RAD51-dsDNA nucleoprotein filament

Human RAD51 is a key protein in the repair of DNA by homologous recombination. Its assembly onto DNA, which induces changes in DNA structure, results in the formation of a nucleoprotein filament that forms the basis of strand exchange. Here, we determine the structural and mechanical properties of R...

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Detalles Bibliográficos
Autores principales:	Lee, Mina, Lipfert, Jan, Sanchez, Humberto, Wyman, Claire, Dekker, Nynke H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737536/ https://www.ncbi.nlm.nih.gov/pubmed/23703213 http://dx.doi.org/10.1093/nar/gkt425

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