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Splicing-coupled 3′ end formation requires a terminal splice acceptor site, but not intron excision
Splicing of human pre-mRNA is reciprocally coupled to 3′ end formation by terminal exon definition, which occurs co-transcriptionally. It is required for the final maturation of most human pre-mRNAs and is therefore important to understand. We have used several strategies to block splicing at specif...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737548/ https://www.ncbi.nlm.nih.gov/pubmed/23716637 http://dx.doi.org/10.1093/nar/gkt446 |