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Sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma
INTRODUCTION: Radical surgery is the “gold standard” for treatment of invasive penile carcinoma but very poor aesthetic, functional and psychological outcomes have been reported. Our purpose was to assess the impact of organ potency-sparing surgery in locally confined carcinoma of the penis. MATERIA...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737667/ https://www.ncbi.nlm.nih.gov/pubmed/23956513 http://dx.doi.org/10.4103/0970-1591.114033 |
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author | Gulino, Gaetano Sasso, Francesco Palermo, Giuseppe D’Onofrio, Alfonso Racioppi, Marco Sacco, Emilio Pinto, Francesco Antonucci, Michele D’Addessi, Alessandro Bassi, PierFrancesco |
author_facet | Gulino, Gaetano Sasso, Francesco Palermo, Giuseppe D’Onofrio, Alfonso Racioppi, Marco Sacco, Emilio Pinto, Francesco Antonucci, Michele D’Addessi, Alessandro Bassi, PierFrancesco |
author_sort | Gulino, Gaetano |
collection | PubMed |
description | INTRODUCTION: Radical surgery is the “gold standard” for treatment of invasive penile carcinoma but very poor aesthetic, functional and psychological outcomes have been reported. Our purpose was to assess the impact of organ potency-sparing surgery in locally confined carcinoma of the penis. MATERIALS AND METHODS: We evaluated retrospectively 42 patients with early penile cancer (Ta,T1,T2), treated with glandulectomy and glanduloplasty with urethral mucosa and sparing of cavernosal apexes, or glandulectomy and limited apical resection in cases of Stage T2. Sexual function, ejaculation and libido were evaluated with an IIEF-15 questionnaire before the appearance of neoplasia (about three months before the surgery) and six months after surgery. Quality of life was evaluated by the Bigelow-Young questionnaire. The scores relating to two weeks prior to the surgery have been compared to those obtained six months after surgery. The statistical analysis was conducted using t-Student for repeated measures and analysis of variance. RESULTS: Six months after surgery 73% of patients reported spontaneous rigid erections, 60% coital activity while 76% of the group treated with urethral glanduloplasty reported normal ejaculation and orgasm, regained an average of 35 days after surgery. The average IIEF-15 scores reported in the entire series in the domains of erection, libido and coital activity of the pre-cancer period were not statistically different than those recorded six months after surgery. In the group treated with glandular reconstruction, pre-and postoperative IIEF-15 mean scores related to ejaculation and orgasm domains were not significantly different. Mean scores of Bigelow-Young questionnaires related to sexual pleasure, familial, social and professional relationships showed significant improvement after surgery. CONCLUSIONS: Potency sparing-sparing surgical treatments have a positive impact on a wide spectrum of the patient's life including family relationships, and social and working conditions. |
format | Online Article Text |
id | pubmed-3737667 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37376672013-08-16 Sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma Gulino, Gaetano Sasso, Francesco Palermo, Giuseppe D’Onofrio, Alfonso Racioppi, Marco Sacco, Emilio Pinto, Francesco Antonucci, Michele D’Addessi, Alessandro Bassi, PierFrancesco Indian J Urol Original Article INTRODUCTION: Radical surgery is the “gold standard” for treatment of invasive penile carcinoma but very poor aesthetic, functional and psychological outcomes have been reported. Our purpose was to assess the impact of organ potency-sparing surgery in locally confined carcinoma of the penis. MATERIALS AND METHODS: We evaluated retrospectively 42 patients with early penile cancer (Ta,T1,T2), treated with glandulectomy and glanduloplasty with urethral mucosa and sparing of cavernosal apexes, or glandulectomy and limited apical resection in cases of Stage T2. Sexual function, ejaculation and libido were evaluated with an IIEF-15 questionnaire before the appearance of neoplasia (about three months before the surgery) and six months after surgery. Quality of life was evaluated by the Bigelow-Young questionnaire. The scores relating to two weeks prior to the surgery have been compared to those obtained six months after surgery. The statistical analysis was conducted using t-Student for repeated measures and analysis of variance. RESULTS: Six months after surgery 73% of patients reported spontaneous rigid erections, 60% coital activity while 76% of the group treated with urethral glanduloplasty reported normal ejaculation and orgasm, regained an average of 35 days after surgery. The average IIEF-15 scores reported in the entire series in the domains of erection, libido and coital activity of the pre-cancer period were not statistically different than those recorded six months after surgery. In the group treated with glandular reconstruction, pre-and postoperative IIEF-15 mean scores related to ejaculation and orgasm domains were not significantly different. Mean scores of Bigelow-Young questionnaires related to sexual pleasure, familial, social and professional relationships showed significant improvement after surgery. CONCLUSIONS: Potency sparing-sparing surgical treatments have a positive impact on a wide spectrum of the patient's life including family relationships, and social and working conditions. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3737667/ /pubmed/23956513 http://dx.doi.org/10.4103/0970-1591.114033 Text en Copyright: © Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Gulino, Gaetano Sasso, Francesco Palermo, Giuseppe D’Onofrio, Alfonso Racioppi, Marco Sacco, Emilio Pinto, Francesco Antonucci, Michele D’Addessi, Alessandro Bassi, PierFrancesco Sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma |
title | Sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma |
title_full | Sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma |
title_fullStr | Sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma |
title_full_unstemmed | Sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma |
title_short | Sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma |
title_sort | sexual outcomes after organ potency-sparing surgery and glans reconstruction in patients with penile carcinoma |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737667/ https://www.ncbi.nlm.nih.gov/pubmed/23956513 http://dx.doi.org/10.4103/0970-1591.114033 |
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