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Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico

Cellular systems are generally robust against fluctuations of intracellular parameters such as gene expression level. However, little is known about expression limits of genes required to halt cellular systems. In this study, using the fission yeast Schizosaccharomyces pombe, we developed a genetic...

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Detalles Bibliográficos
Autores principales: Moriya, Hisao, Chino, Ayako, Kapuy, Orsolya, Csikász-Nagy, Attila, Novák, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737731/
https://www.ncbi.nlm.nih.gov/pubmed/22146300
http://dx.doi.org/10.1038/msb.2011.91