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Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation

For a successful yet controlled immune response, cells need to specifically destabilize inflammatory mRNAs but prevent premature removal of those still used. The regulatory circuits controlling quality and timing in the global inflammatory mRNA decay are not understood. Here, we show that the mRNA-d...

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Detalles Bibliográficos
Autores principales: Kratochvill, Franz, Machacek, Christian, Vogl, Claus, Ebner, Florian, Sedlyarov, Vitaly, Gruber, Andreas R, Hartweger, Harald, Vielnascher, Raimund, Karaghiosoff, Marina, Rülicke, Thomas, Müller, Mathias, Hofacker, Ivo, Lang, Roland, Kovarik, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737733/
https://www.ncbi.nlm.nih.gov/pubmed/22186734
http://dx.doi.org/10.1038/msb.2011.93