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Chaperone-assisted proteostasis is essential for mechanotransduction in mammalian cells
Maintaining the dynamic proteome of a living cell in the face of an ever-changing environment depends on a fine-tuned balance of protein synthesis and protein degradation. Molecular chaperones exert key functions during protein homeostasis (proteostasis). They associate with nonnative client protein...
Autores principales: | Ulbricht, Anna, Arndt, Verena, Höhfeld, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737759/ https://www.ncbi.nlm.nih.gov/pubmed/23986815 http://dx.doi.org/10.4161/cib.24925 |
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